Colon cancer–derived conditioned medium induces differentiation of THP-1 monocytes into a mixed population of M1/M2 cells

Macrophages play an important role in the immune response and in the maintenance of tissue homeostasis. It is well known that many tumors recruit monocytes from circulation and influence their differentiation, mainly into suppressive M2-like subsets. Since there are contradictory data concerning the...

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Bibliographic Details
Main Authors: Katarzyna Sawa-Wejksza, Adrianna Dudek, Marta Lemieszek, Katarzyna Kaławaj, Martyna Kandefer-Szerszeń
Format: Article
Language:English
Published: IOS Press 2018-08-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428318797880