The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

Age is one of the strongest risk factors for severe illness from COVID-19. By integrating human lung transcriptomes with experimental data on SARS-CoV-2, the authors pinpoint specific age-associated factors that could contribute to the heightened severity of COVID-19 in older populations.

Bibliographic Details
Main Authors: Ryan D. Chow, Medha Majety, Sidi Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-20323-9