Genetic Mosaics and the Germ Line Lineage

Genetic mosaics provide information about cellular lineages that is otherwise difficult to obtain, especially in humans. De novo mutations act as cell markers, allowing the tracing of developmental trajectories of all descendants of the cell in which the new mutation arises. De novo mutations may ar...

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Bibliographic Details
Main Authors: Mark E. Samuels, Jan M. Friedman
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:Genes
Subjects:
Online Access:http://www.mdpi.com/2073-4425/6/2/216