249 TP53 mutation has high prevalence and is correlated with larger and poorly differentiated HCC in Brazilian patients

<p>Abstract</p> <p>Background</p> <p>Ser-249 TP53 mutation (249<sup>Ser</sup>) is a molecular evidence for aflatoxin-related carcinogenesis in Hepatocellular Carcinoma (HCC) and it is frequent in some African and Asian regions, but it is unusual in Western c...

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Main Authors: Paranaguá-Vezozzo Denise C, Scapulatempo Cristovan, Mello Evandro S, do Carmo Eliane P, de Souza Marcelo MT, Nita Marcelo E, Ono-Nita Suzane K, Nogueira Jeronimo A, Carrilho Flair J, Alves Venancio AF
Format: Article
Language:English
Published: BMC 2009-06-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/204