Exposure to Vicarious Social Defeat Stress and Western-Style Diets During Adolescence Leads to Physiological Dysregulation, Decreases in Reward Sensitivity, and Reduced Antidepressant Efficacy in Adulthood

Exposure to Vicarious Social Defeat Stress and Western-Style Diets During Adolescence Leads to Physiological Dysregulation, Decreases in Reward Sensitivity, and Reduced Antidepressant Efficacy in Adulthood

A dramatic increase in the prevalence of major depression and diet-related disorders in adolescents has been observed over several decades, yet the mechanisms underlying this comorbidity have only recently begun to be elucidated. Exposure to western-style diet (WSD), high in both fats (45% kcal) and...

Full description

Bibliographic Details
Main Authors: Omar K. Sial, Tamara Gnecco, Astrid M. Cardona-Acosta, Emily Vieregg, Ernesto A. Cardoso, Lyonna F. Parise, Carlos A. Bolaños-Guzmán
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Neuroscience
Subjects:
adolescence
early-life stress
western-style
high-fat diet
depression
antidepressant efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.701919/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.701919/full

Similar Items