Effects of Mild Hypothermia on Superoxide Anion Production, Superoxide Dismutase Expression, and Activity Following Transient Focal Cerebral Ischemia

Effects of Mild Hypothermia on Superoxide Anion Production, Superoxide Dismutase Expression, and Activity Following Transient Focal Cerebral Ischemia

Following a transient ischemic insult there is a marked increase in free radical (FR) production within the first 10–15 min of reperfusion and again at the peak of the inflammatory process. Hypothermia decreases lipid peroxidation following global ischemia, raising the possibility that it may act by...

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Bibliographic Details
Main Authors: Carolina M. Maier, Guo Hua Sun, Danye Cheng, Midori A. Yenari, Pak H. Chan, Gary K. Steinberg
Format: Article
Language:English
Published: Elsevier 2002-10-01
Series:Neurobiology of Disease
Subjects:
hypothermia
cerebral ischemia
superoxide anion
superoxide dismutase
hydroethidine
free radicals
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102905139

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http://www.sciencedirect.com/science/article/pii/S0969996102905139

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