Old Drugs with New Tricks: Efficacy of Fluoroquinolones to Suppress Replication of Flaviviruses

Old Drugs with New Tricks: Efficacy of Fluoroquinolones to Suppress Replication of Flaviviruses

Repurposing FDA-approved compounds could provide the fastest route to alleviate the burden of disease caused by flaviviruses. In this study, three fluoroquinolones, enoxacin, difloxacin and ciprofloxacin, curtailed replication of flaviviruses Zika (ZIKV), dengue (DENV), Langat (LGTV) and Modoc (MODV...

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Bibliographic Details
Main Authors: Stacey L. P. Scroggs, Christy C. Andrade, Ramesh Chinnasamy, Sasha R. Azar, Erin E. Schirtzinger, Erin I. Garcia, Jeffrey B. Arterburn, Kathryn A. Hanley, Shannan L. Rossi
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Viruses
Subjects:
Zika virus
dengue virus
flavivirus
antiviral
fluoroquinolone
ciprofloxacin
Online Access:https://www.mdpi.com/1999-4915/12/9/1022

Internet

https://www.mdpi.com/1999-4915/12/9/1022

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