Genetic, functional and molecular features of glucocorticoid receptor binding.

Glucocorticoids (GCs) are key mediators of stress response and are widely used as pharmacological agents to treat immune diseases, such as asthma and inflammatory bowel disease, and certain types of cancer. GCs act mainly by activating the GC receptor (GR), which interacts with other transcription f...

Full description

Bibliographic Details
Main Authors: Francesca Luca, Joseph C Maranville, Allison L Richards, David B Witonsky, Matthew Stephens, Anna Di Rienzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3640037?pdf=render