Novel acetylcholinesterase target site for malaria mosquito control.
Current anticholinesterase pesticides were developed during World War II and are toxic to mammals because they target a catalytic serine residue of acetylcholinesterases (AChEs) in insects and in mammals. A sequence analysis of AChEs from 73 species and a three-dimensional model of a malaria-carryin...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2006-12-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0000058 |