Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome

Up-regulated FHL2 inhibits ovulation through interacting with androgen receptor and ERK1/2 in polycystic ovary syndrome

Background: The ovulatory dysfunction mechanisms underlying polycystic ovary syndrome (PCOS) are not completely understood. There is no effective therapy for PCOS so far. Methods: We measured the expression of four and a half LIM domain 2 (FHL2) and other related-genes in human granulosa cells (hGCs...

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Bibliographic Details
Main Authors: Ruiqiong Zhou, Shang Li, Jiansheng Liu, Hasiximuke Wu, Guangxin Yao, Yun Sun, Zi-Jiang Chen, Weiping Li, Yanzhi Du
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420300104

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http://www.sciencedirect.com/science/article/pii/S2352396420300104

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