Ibandronate Treatment Before and After Implant Insertion Impairs Osseointegration in Aged Rats with Ovariectomy Induced Osteoporosis

Ibandronate Treatment Before and After Implant Insertion Impairs Osseointegration in Aged Rats with Ovariectomy Induced Osteoporosis

Abstract Excessive decreases in bone volume (BV) and bone mineral density (BMD) can lead to osteoporosis, potentially hindering implant osseointegration. Bisphosphonates are commonly used to combat osteoporosis by slowing osteoclast‐mediated resorption; however, functional osteoclasts are integral t...

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Bibliographic Details
Main Authors: Ethan M. Lotz, David J. Cohen, Regan A. Ellis, Jennifer S. Wayne, Zvi Schwartz, Barbara D. Boyan
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:JBMR Plus
Subjects:
Osseointegration
Osteoporosis
Bisphosphonate
Rat
Titanium
Online Access:https://doi.org/10.1002/jbm4.10184

Internet

https://doi.org/10.1002/jbm4.10184

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