The Transcription Regulator Patz1 Is Essential for Neural Stem Cell Maintenance and Proliferation

The Transcription Regulator Patz1 Is Essential for Neural Stem Cell Maintenance and Proliferation

Proper regulation of neurogenesis, the process by which new neurons are generated from neural stem and progenitor cells (NS/PCs), is essential for embryonic brain development and adult brain function. The transcription regulator Patz1 is ubiquitously expressed in early mouse embryos and has a key ro...

Full description

Bibliographic Details
Main Authors:	Sara Mancinelli, Michela Vitiello, Maria Donnini, Francesca Mantile, Giuseppe Palma, Antonio Luciano, Claudio Arra, Laura Cerchia, Giovanna Lucia Liguori, Monica Fedele
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-04-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	neurogenesis neural stem cells PATZ1 knockout mice neurosphere assay subventricular zone
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.657149/full

Similar Items

Loss of One or Two PATZ1 Alleles Has a Critical Role in the Progression of Thyroid Carcinomas Induced by the RET/PTC1 Oncogene
by: Mario Monaco, et al.
Published: (2018-03-01)

The POZ/BTB and AT-Hook Containing Zinc Finger 1 (PATZ1) Transcription Regulator: Physiological Functions and Disease Involvement
by: Monica Fedele, et al.
Published: (2017-11-01)

PATZ1 Is Overexpressed in Pediatric Glial Tumors and Correlates with Worse Event-Free Survival in High-grade Gliomas
by: Annalisa Passariello, et al.
Published: (2019-10-01)

Dual Oncogenic/Anti-Oncogenic Role of PATZ1 in FRTL5 Rat Thyroid Cells Transformed by the <i>Ha-Ras<sup>V12</sup></i> Oncogene
by: Michela Vitiello, et al.
Published: (2019-02-01)

Effects of β-sitosterol oral administration on the proliferation and differentiation of neural stem cells
by: Azadeh Hamedi, et al.
Published: (2014-05-01)

The male sex pheromone darcin stimulates hippocampal neurogenesis and cell proliferation in the subventricular zone in female mice
by: Emma eHoffman, et al.
Published: (2015-04-01)

PATZ1 (MAZR) Co-occupies Genomic Sites With p53 and Inhibits Liver Cancer Cell Proliferation via Regulating p27
by: Zhen Long Ng, et al.
Published: (2021-02-01)

The Postnatal Subventricular Zone: A Source of New Cells in This Old Brain
by: Angélique Bordey
Published: (2005-01-01)

Proliferation rate and differentiation potential are independent during the transition from neurogenesis to gliogenesis in the mouse embryonic spinal cord
by: Leonora Olivos-Cisneros, et al.
Published: (2021-06-01)

Environmental enrichment, age and PPARα interact to regulate proliferation in neurogenic niches
by: Margarita ePerez-Martin, et al.
Published: (2016-03-01)

Decreased Proliferation in the Neurogenic Niche, Disorganized Neuroblast Migration, and Increased Oligodendrogenesis in Adult Netrin-5-Deficient Mice
by: Shunsuke Ikegaya, et al.
Published: (2020-11-01)

Neural stem cell isolation and culture from C57BL/6 mice
by: S Koirala, et al.
Published: (2015-07-01)

Astrocyte-Secreted Factors Selectively Alter Neural Stem and Progenitor Cell Proliferation in the Fragile X Mouse
by: Mary eSourial, et al.
Published: (2016-05-01)

Systematic Review of Nicotine Exposure’s Effects on Neural Stem and Progenitor Cells
by: Arrin C. Brooks, et al.
Published: (2021-01-01)

Involvement of calpains in adult neurogenesis: implications for stroke
by: Vanessa Mendes Machado, et al.
Published: (2015-02-01)

Activated regulatory T cell regulates neural stem cell proliferation in the subventricular zone of normal and ischemic mouse brain through interleukin 10
by: Jixian eWang, et al.
Published: (2015-09-01)

A Simplified Method For Isolation and Culture of Neural Stem Cells From Adult Mice Brain: in Vitro
by: Nashaat G. Mustafa, et al.
Published: (2013-09-01)

Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease
by: Jessica M. Simpson, et al.
Published: (2011-02-01)

Isolating Globose Basal Stem Cells from Albino Wistar Rats Using a Highly Specific Monoclonal Antibody
by: Avinash Thakur, et al.
Published: (2013-11-01)

Differential Roles of Environmental Enrichment in Alzheimer’s Type of Neurodegeneration and Physiological Aging
by: Vladimir V. Salmin, et al.
Published: (2017-07-01)

Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia
by: Urs Fisch, et al.
Published: (2020-01-01)

Age-Dependent Increase of Brain Copper Levels and Expressions of Copper Regulatory Proteins in the Subventricular Zone and Choroid Plexus
by: Sherleen eFu, et al.
Published: (2015-06-01)

Neonatal hypoxic–ischemic injury increases forebrain subventricular zone neurogenesis in the mouse
by: Jennifer M Plane, et al.
Published: (2004-08-01)

HPG-Dependent Peri-Pubertal Regulation of Adult Neurogenesis in Mice
by: Sara Trova, et al.
Published: (2020-11-01)

Suppressor of Fused regulates the proliferation of postnatal neural stem and precursor cells via a Gli3-dependent mechanism
by: Hector G. Gomez, et al.
Published: (2019-06-01)

miR-30 Family miRNAs Mediate the Effect of Chronic Social Defeat Stress on Hippocampal Neurogenesis in Mouse Depression Model
by: Nitin Khandelwal, et al.
Published: (2019-08-01)

Brain-Derived Neurotrophic Factor (BDNF) Role in Cannabinoid-Mediated Neurogenesis
by: Filipa Fiel Ferreira, et al.
Published: (2018-11-01)

Cell-specific expression of Epac2 in the subventricular and subgranular zones
by: Hyunhyo Seo, et al.
Published: (2019-12-01)

New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis.
by: Maria Francisca eEiriz, et al.
Published: (2014-06-01)

Implications of irradiating the subventricular zone stem cell niche
by: Vivian Capilla-Gonzalez, et al.
Published: (2016-03-01)

Estradiol and the Development of the Cerebral Cortex: An Unexpected Role?
by: Matthew C. S. Denley, et al.
Published: (2018-05-01)

Editorial: Neural Stem Cells of the Subventricular Zone: From Neurogenesis to Glioblastoma Origin
by: Esperanza R. Matarredona, et al.
Published: (2021-09-01)

Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis
by: Akiko Terauchi, et al.
Published: (2017-12-01)

Cell proliferation in the subventricular zone by synthetic murine pheromones.
by: Sachiko eKoyama, et al.
Published: (2013-08-01)

Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids
by: Stefano eFarioli-Vecchioli, et al.
Published: (2014-04-01)

Rapid generation of sub-type, region-specific neurons and neural networks from human pluripotent stem cell-derived neurospheres
by: Aynun N. Begum, et al.
Published: (2015-11-01)

The responses of neural stem cells to the level of GSK-3 depend on the tissue of origin
by: Tamara Holowacz, et al.
Published: (2013-06-01)

The generation of oligodendroglial cells is preserved in the rostral migratory stream during aging
by: Vivian eCapilla-Gonzalez, et al.
Published: (2013-09-01)

Bone morphogenetic protein dominantly suppresses epidermal growth factor-induced proliferative expansion of adult forebrain neural precursors
by: Sandra Evelyne Joppé, et al.
Published: (2015-10-01)

Persistent Decreases in Adult Subventricular and Hippocampal Neurogenesis Following Adolescent Intermittent Ethanol Exposure
by: Wen Liu, et al.
Published: (2017-08-01)