The Transcription Regulator Patz1 Is Essential for Neural Stem Cell Maintenance and Proliferation

The Transcription Regulator Patz1 Is Essential for Neural Stem Cell Maintenance and Proliferation

Proper regulation of neurogenesis, the process by which new neurons are generated from neural stem and progenitor cells (NS/PCs), is essential for embryonic brain development and adult brain function. The transcription regulator Patz1 is ubiquitously expressed in early mouse embryos and has a key ro...

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Bibliographic Details
Main Authors: Sara Mancinelli, Michela Vitiello, Maria Donnini, Francesca Mantile, Giuseppe Palma, Antonio Luciano, Claudio Arra, Laura Cerchia, Giovanna Lucia Liguori, Monica Fedele
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
neurogenesis
neural stem cells
PATZ1
knockout mice
neurosphere assay
subventricular zone
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.657149/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.657149/full

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