Long-term outcomes of gene therapy for the treatment of Leber's hereditary optic neuropathy

Leber's hereditary optic neuropathy (LHON) is a disease that leads to blindness. Gene therapy has been investigated with some success, and could lead to important advancements in treating LHON. This was a prospective, open-label trial involving 9 LHON patients at Tongji Hospital, Wuhan, China,...

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Bibliographic Details
Main Authors: Shuo Yang, Si-qi Ma, Xing Wan, Heng He, Han Pei, Min-jian Zhao, Chen Chen, Dao-wen Wang, Xiao-yan Dong, Jia-jia Yuan, Bin Li
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416303073