Isoflurane and Sevoflurane Induce Severe Hepatic Insulin Resistance in a Canine Model.

INTRODUCTION:Anesthesia induces insulin resistance, which may contribute to elevated blood glucose and adverse post-operative outcomes in critically ill patients, and impair glycemic control in surgical patients with diabetes. However, little is known about the mechanisms by which anesthesia impairs...

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Bibliographic Details
Main Authors: Stella P Kim, Josiane L Broussard, Cathryn M Kolka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5089720?pdf=render