The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation

The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation

Many, if not all, environmental pollutants/chemicals and infectious agents increase intracellular levels of reactive oxygen species (ROS) at the site of exposure. ROS not only function as intracellular signaling entities, but also induce damage to cellular molecules including DNA. Among the several...

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Bibliographic Details
Main Authors: Xueqing Ba, Leopoldo Aguilera-Aguirre, Qura Tul Ain Nmi Rashid, Attila Bacsi, Zsolt Radak, Sanjiv Sur, Koa Hosoki, Muralidhar L. Hegde, Istvan Boldogh
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:International Journal of Molecular Sciences
Subjects:
OGG1
DNA base excision repair
8-oxoG base
small GTPases
inflammation
Online Access:http://www.mdpi.com/1422-0067/15/9/16975

Internet

http://www.mdpi.com/1422-0067/15/9/16975

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