Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis.
The stem-cell leukemia (SCL, also known as TAL1) gene encodes a basic helix-loop-helix transcription factor that is essential for the initiation of primitive and definitive hematopoiesis, erythrocyte and megakarocyte differentiation, angiogenesis, and astrocyte development. Here we report that the z...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-05-01
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Series: | PLoS Biology |
Online Access: | http://europepmc.org/articles/PMC1858710?pdf=render |