Neurovascular and Neurometabolic Derailment in Aging and Alzheimer’s Disease

The functional and structural integrity of the brain requires local adjustment of blood flow and regulated delivery of metabolic substrates to meet the metabolic demands imposed by neuronal activation. This process – neurovascular coupling – and ensued alterations of glucose and oxygen metabolism -...

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Bibliographic Details
Main Authors: Cátia eLourenço, Ana eLedo, Cândida eDias, Rui M Barbosa, João eLaranjinha
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnagi.2015.00103/full