FOXR2 Interacts with MYC to Promote Its Transcriptional Activities and Tumorigenesis

By combining the results of a large-scale proteomic analysis of the human transcription factor interaction network with knowledge databases, we identified FOXR2 as one of the top-ranked candidate proto-oncogenes. Here, we show that FOXR2 forms a stable complex with MYC and MAX and subsequently regul...

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Bibliographic Details
Main Authors: Xu Li, Wenqi Wang, Yuanxin Xi, Min Gao, MyKim Tran, Kathryn E. Aziz, Jun Qin, Wei Li, Junjie Chen
Format: Article
Language:English
Published: Elsevier 2016-07-01
Series:Cell Reports
Subjects:
MYC
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716307239