Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein.

Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein.

Antiviral drug resistance for influenza therapies remains a concern due to the high prevalence of H1N1 2009 seasonal influenza isolates which display H274Y associated oseltamivir-resistance. Furthermore, the emergence of novel H1N1 raises the potential that additional reassortments can occur, result...

Full description

Bibliographic Details
Main Authors: Gallen B Triana-Baltzer, Larisa V Gubareva, Alexander I Klimov, David F Wurtman, Ronald B Moss, Maria Hedlund, Jeffrey L Larson, Robert B Belshe, Fang Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2770896?pdf=render

Internet

http://europepmc.org/articles/PMC2770896?pdf=render

Similar Items