Four types of scrapie in goats differentiated from each other and bovine spongiform encephalopathy by biochemical methods

Abstract Scrapie in goats has been known since 1942, the archetype of prion diseases in which only prion protein (PrP) in misfolded state (PrPSc) acts as infectious agent with fatal consequence. Emergence of bovine spongiform encephalopathy (BSE) with its zoonotic behaviour and detection in goats en...

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Main Authors: Jan P. M. Langeveld, Laura Pirisinu, Jorg G. Jacobs, Maria Mazza, Isabelle Lantier, Stéphanie Simon, Olivier Andréoletti, Cristina Acin, Elena Esposito, Christine Fast, Martin Groschup, Wilfred Goldmann, John Spiropoulos, Theodoros Sklaviadis, Frederic Lantier, Loukia Ekateriniadou, Penelope Papasavva-Stylianou, Lucien J. M. van Keulen, Pier-Luigi Acutis, Umberto Agrimi, Alex Bossers, Romolo Nonno
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-019-0718-z