Picropodophyllotoxin, an Epimer of Podophyllotoxin, Causes Apoptosis of Human Esophageal Squamous Cell Carcinoma Cells Through ROS-Mediated JNK/P38 MAPK Pathways

Picropodophyllotoxin, an Epimer of Podophyllotoxin, Causes Apoptosis of Human Esophageal Squamous Cell Carcinoma Cells Through ROS-Mediated JNK/P38 MAPK Pathways

Esophageal squamous cell carcinoma (ESCC), a major histologic type of esophageal cancer, is one of the frequent causes of cancer-related death worldwide. Picropodophyllotoxin (PPT) is the main component of <i>Podophyllum </i><i>hexandrum</i> root with antitumor activity via a...

Full description

Bibliographic Details
Main Authors: Ah-Won Kwak, Goo Yoon, Mee-Hyun Lee, Seung-Sik Cho, Jung-Hyun Shim, Jung-Il Chae
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
picropodophyllotoxin
esophageal squamous cancer
apoptosis
p38
JNK
Online Access:https://www.mdpi.com/1422-0067/21/13/4640

Internet

https://www.mdpi.com/1422-0067/21/13/4640

Similar Items