$Significance of MDR1 and multiple drug resistance in refractory human epileptic brain$

Significance of MDR1 and multiple drug resistance in refractory human epileptic brain

<p>Abstract</p> <p>Background</p> <p>The multiple drug resistance protein (MDR1/P-glycoprotein) is overexpressed in glia and blood-brain barrier (BBB) endothelium in drug refractory human epileptic tissue. Since various antiepileptic drugs (AEDs) can act as substrates f...

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Bibliographic Details
Main Authors:	Dini Gabriele, Bingaman William, Moddel Gabriel, Cucullo Luca, Kight Kelly M, Hallene Kerri L, Marchi Nicola, Vezzani Annamaria, Janigro Damir
Format:	Article
Language:	English
Published:	BMC 2004-10-01
Series:	BMC Medicine
Online Access:	http://www.biomedcentral.com/1741-7015/2/37

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