Significance of MDR1 and multiple drug resistance in refractory human epileptic brain
<p>Abstract</p> <p>Background</p> <p>The multiple drug resistance protein (MDR1/P-glycoprotein) is overexpressed in glia and blood-brain barrier (BBB) endothelium in drug refractory human epileptic tissue. Since various antiepileptic drugs (AEDs) can act as substrates f...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2004-10-01
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| Series: | BMC Medicine |
| Online Access: | http://www.biomedcentral.com/1741-7015/2/37 |