Expression and Function of the Endocannabinoid Modulating Enzymes Fatty Acid Amide Hydrolase and N-Acylphosphatidylethanolamine-Specific Phospholipase D in Endometrial Carcinoma

Expression and Function of the Endocannabinoid Modulating Enzymes Fatty Acid Amide Hydrolase and N-Acylphosphatidylethanolamine-Specific Phospholipase D in Endometrial Carcinoma

Background: The concentrations of three N-acylethanolamines (NAEs), anandamide (AEA), N-oleoylethanolamide (OEA), and N-palmitylethanolamide (PEA) are increased in the endometria of women with endometrial cancer (EC). It is widely accepted that plasma levels of these three NAEs are regulated by the...

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Bibliographic Details
Main Authors: Thangesweran Ayakannu, Anthony H. Taylor, Monica Bari, Nicoletta Mastrangelo, Mauro Maccarrone, Justin C. Konje
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Oncology
Subjects:
endocannabinoids
endometrial cancer
fatty acid amide hydrolase
gene expression
immunohistochemistry
N-acylphoshatidylethanolmine-specific phospholipase D
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.01363/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.01363/full

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