A secretion biosensor for monitoring Sec-dependent protein export in Corynebacterium glutamicum

A secretion biosensor for monitoring Sec-dependent protein export in Corynebacterium glutamicum

Abstract Background In recent years, the industrial workhorse Corynebacterium glutamicum has gained increasing interest as a host organism for the secretory production of heterologous proteins. Generally, the yield of a target protein in the culture supernatant depends on a multitude of interdepende...

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Bibliographic Details
Main Authors: Sarah Jurischka, Astrid Bida, Doris Dohmen-Olma, Britta Kleine, Janko Potzkei, Stephan Binder, Georg Schaumann, Patrick J. Bakkes, Roland Freudl
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Microbial Cell Factories
Subjects:
Corynebacterium glutamicum
Heterologous protein production
Sec pathway
Secretion biosensor
Signal peptide variation
FACS analysis
Online Access:https://doi.org/10.1186/s12934-019-1273-z

Internet

https://doi.org/10.1186/s12934-019-1273-z

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