Inhibition of Prostate Smooth Muscle Contraction by Inhibitors of Polo-Like Kinases

Inhibition of Prostate Smooth Muscle Contraction by Inhibitors of Polo-Like Kinases

Background: Prostate smooth muscle contraction plays an important role for pathophysiology and treatment of male lower urinary tract symptoms (LUTS) but is incompletely understood. Because the efficacy of available medication is limited, novel options and improved understanding of prostate smooth mu...

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Bibliographic Details
Main Authors: Martin Hennenberg, Paul Kuppermann, Qingfeng Yu, Annika Herlemann, Alexander Tamalunas, Yiming Wang, Beata Rutz, Anna Ciotkowska, Frank Strittmatter, Christian G. Stief, Christian Gratzke
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Physiology
Subjects:
benign prostatic hyperplasia (BPH)
lower urinary tract symptoms (LUTS)
prostate smooth muscle contraction
α1-adrenoceptor
α1-blocker
polo-like kinase (PLK)
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00734/full

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https://www.frontiersin.org/article/10.3389/fphys.2018.00734/full

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