Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila

Selection and characterization of alanine racemase inhibitors against Aeromonas hydrophila

Abstract Background Combining experimental and computational screening methods has been of keen interest in drug discovery. In the present study, we developed an efficient screening method that has been used to screen 2100 small-molecule compounds for alanine racemase Alr-2 inhibitors. Results We id...

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Bibliographic Details
Main Authors: Yaping Wang, Chao Yang, Wen Xue, Ting Zhang, Xipei Liu, Jiansong Ju, Baohua Zhao, Dong Liu
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Microbiology
Subjects:
Aeromonas hydrophila
Alanine racemase
Inhibitor
Molecular docking
Online Access:http://link.springer.com/article/10.1186/s12866-017-1010-x

Internet

http://link.springer.com/article/10.1186/s12866-017-1010-x

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