Single Dose Study Assessing the Pharmacokinetic and Metabolic Profile of Alverine Citrate in Healthy Volunteers

Single Dose Study Assessing the Pharmacokinetic and Metabolic Profile of Alverine Citrate in Healthy Volunteers

Alverine citrate is a spasmolytic commonly prescribed in conditions such as irritable bowel syndrome, painful diverticular disease of the colon, and primary dysmenorrhea. While clinical efficacy data on alverine alone or in combination with simethicone is freely available, surprisingly little inform...

Full description

Bibliographic Details
Main Authors: Simona Rizea-Savu, Simona Nicoleta Duna, Roxana Colette Sandulovici
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Pharmacology
Subjects:
alverine citrate
4-hydroxy alverine
4-hydroxy alverine glucuronide
N-desethyl alverine
pharmacokinetics
in-vivo metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2020.620451/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2020.620451/full

Similar Items