Chromatin organization changes during the establishment and maintenance of the postmitotic state

Abstract Background Genome organization changes during development as cells differentiate. Chromatin motion becomes increasingly constrained and heterochromatin clusters as cells become restricted in their developmental potential. These changes coincide with slowing of the cell cycle, which can also...

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Bibliographic Details
Main Authors: Yiqin Ma, Laura Buttitta
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Epigenetics & Chromatin
Subjects:
E2F
Online Access:http://link.springer.com/article/10.1186/s13072-017-0159-8