Gradual withdrawal of remifentanil delays initial post-operative analgesic demand after thyroid surgery; double-blinded, randomized controlled trial

Abstract Background Mismanagement of remifentanil leads to severe side effects such as opioid-induced tolerance and hyperalgesia. Recently studies revealed an alternative withdrawal method to limit these side effects. A gradual withdrawal of remifentanil seems to be associated with less pain. The hy...

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Bibliographic Details
Main Authors: Sarah Saxena, Kimberly Gonsette, Willy Terram, Isabelle Huybrechts, Daniel A. Nahrwold, Matteo Cappello, Luc Barvais, Edgard Engelman
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Anesthesiology
Online Access:http://link.springer.com/article/10.1186/s12871-019-0731-9