Cigarette and IL-17A synergistically induce bronchial epithelial-mesenchymal transition via activating IL-17R/NF-κB signaling

Cigarette and IL-17A synergistically induce bronchial epithelial-mesenchymal transition via activating IL-17R/NF-κB signaling

Abstract Background IL-17A directly induces epithelial-mesenchymal transition (EMT) in alveolar epithelial cells. It could coordinate with cigarette smoke extract (CSE) to promote proliferation of bronchial epithelial cells. In this study, we aim to explore the direct effect of IL-17A and CSE on EMT...

Full description

Bibliographic Details
Main Authors: Libing Ma, Ming Jiang, Xiaoli Zhao, Jingyi Sun, Qilu Pan, Shuyuan Chu
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Pulmonary Medicine
Subjects:
Epithelial-mesenchymal transition
Bronchial epithelial cell
IL-17
NF-κB
Cigarette smoke extract
Online Access:https://doi.org/10.1186/s12890-020-1057-6

Internet

https://doi.org/10.1186/s12890-020-1057-6

Similar Items