Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal

Chlorinated lipid species in activated human neutrophils: lipid metabolites of 2-chlorohexadecanal

Neutrophils are important in the host response against invading pathogens. One chemical defense mechanism employed by neutrophils involves the production of myeloperoxidase (MPO)-derived HOCl. 2-Chlorohexadecanal (2-ClHDA) is a naturally occurring lipid product of HOCl targeting the vinyl ether bond...

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Bibliographic Details
Main Authors: Dhanalakshmi S. Anbukumar, Laurie P. Shornick, Carolyn J. Albert, Melissa M. Steward, Raphael A. Zoeller, William L. Neumann, David A. Ford
Format: Article
Language:English
Published: Elsevier 2010-05-01
Series:Journal of Lipid Research
Subjects:
fatty aldehydes
plasmalogens
myeloperoxidase
reactive chlorinating species
hypochlorous acid
inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520410648

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http://www.sciencedirect.com/science/article/pii/S0022227520410648

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