AIB1 sequestration by androgen receptor inhibits estrogen-dependent cyclin D1 expression in breast cancer cells

AIB1 sequestration by androgen receptor inhibits estrogen-dependent cyclin D1 expression in breast cancer cells

Abstract Background Androgens, through their own receptor, play a protective role on breast tumor development and progression and counterbalance estrogen-dependent growth stimuli which are intimately linked to breast carcinogenesis. Methods Cell counting by trypan blu exclusion was used to study and...

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Bibliographic Details
Main Authors: Francesca De Amicis, Chiara Chiodo, Catia Morelli, Ivan Casaburi, Stefania Marsico, Rosalinda Bruno, Diego Sisci, Sebastiano Andò, Marilena Lanzino
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Cancer
Subjects:
Breast cancer
MCF-7
Androgen receptor
Estrogen receptor
Dihydrotestosterone
Estradiol
Online Access:http://link.springer.com/article/10.1186/s12885-019-6262-4

Internet

http://link.springer.com/article/10.1186/s12885-019-6262-4

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