Hypoxia-Driven Immune Escape in the Tumor Microenvironment

The tumor microenvironment is a complex ecosystem comprised of many different cell types, abnormal vasculature and immunosuppressive cytokines. The irregular growth kinetics with which tumors grow leads to increased oxygen consumption and, in turn, hypoxic conditions. Hypoxia has been associated wit...

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Bibliographic Details
Main Authors: Alyssa Vito, Nader El-Sayes, Karen Mossman
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/992