Silver(I) and Copper(II) Complexes of 1,10-Phenanthroline-5,6-Dione Against Phialophora verrucosa: A Focus on the Interaction With Human Macrophages and Galleria mellonella Larvae

Silver(I) and Copper(II) Complexes of 1,10-Phenanthroline-5,6-Dione Against Phialophora verrucosa: A Focus on the Interaction With Human Macrophages and Galleria mellonella Larvae

Phialophora verrucosa is a dematiaceous fungus that causes mainly chromoblastomycosis, but also disseminated infections such as phaeohyphomycosis and mycetoma. These diseases are extremely hard to treat and often refractory to current antifungal therapies. In this work, we have evaluated the effect...

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Bibliographic Details
Main Authors: Marcela Q. Granato, Thaís P. Mello, Renata S. Nascimento, Marcos D. Pereira, Thabatta L. S. A. Rosa, Maria C. V. Pessolani, Malachy McCann, Michael Devereux, Marta H. Branquinha, André L. S. Santos, Lucimar F. Kneipp
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
1,10-phenanthroline-5,6-dione
chromoblastomycosis
dematiaceous fungi
antifungal activity
cellular interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.641258/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2021.641258/full

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