Effect of Reparation of Repeat Sequences in the Human α-Synuclein on Fibrillation Ability
<p>The aggregation and fibrillation of α-synuclein has been implicated as a causative factor in the Parkinson's disease. The hexamer motif KTKEGV is found in each of the seven imperfect repeat sequences in the N-terminal half of α-synuclein. The motif is not fully conser...
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Format: | Article |
Language: | English |
Published: |
Ivyspring International Publisher
2007-01-01
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Series: | International Journal of Biological Sciences |
Online Access: | http://www.biolsci.org/v03p0001.htm |