β-eudesmol but not atractylodin exerts an inhibitory effect on CFTR-mediated chloride transport in human intestinal epithelial cells

β-eudesmol but not atractylodin exerts an inhibitory effect on CFTR-mediated chloride transport in human intestinal epithelial cells

Oriental herbal medicine with the two bioactive constituents, β-eudesmol (BE) and atractylodin (AT), has been used as a remedy for gastrointestinal disorders. There was no scientific evidence reporting their antidiarrheal effect and underpinning mechanisms. Therefore, we aimed to investigate the ant...

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Bibliographic Details
Main Authors: Phuntila Tharabenjasin, Ronaldo P. Ferraris, Kiattawee Choowongkomon, Pawin Pongkorpsakol, Nichakorn Worakajit, Sutthipong Sawasvirojwong, Noel Pabalan, Kesara Na-Bangchang, Chatchai Muanprasat
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Diarrhea
β-eudesmol
CFTR
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221008131

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http://www.sciencedirect.com/science/article/pii/S0753332221008131

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