Impact of Altered Mineral Metabolism on Pathological Cardiac Remodeling in Elevated Fibroblast Growth Factor 23

Impact of Altered Mineral Metabolism on Pathological Cardiac Remodeling in Elevated Fibroblast Growth Factor 23

Clinical and experimental studies indicate a possible link between high serum levels of fibroblast growth factor 23 (FGF23), phosphate, and parathyroid hormone (PTH), deficiency of active vitamin D (1,25D) and klotho with the development of pathological cardiac remodeling, i.e., left ventricular hyp...

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Bibliographic Details
Main Authors: Maren Leifheit-Nestler, Beatrice Richter, Melis Basaran, Julia Nespor, Isabel Vogt, Ioana Alesutan, Jakob Voelkl, Florian Lang, Joerg Heineke, Stefanie Krick, Dieter Haffner
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Endocrinology
Subjects:
fibroblast growth factor 23
klotho deficiency
mineral metabolism
left ventricular hypertrophy
cardiac fibrosis
klotho hypomorphic mice
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00333/full

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https://www.frontiersin.org/article/10.3389/fendo.2018.00333/full

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