Similar structures but different roles - An updated perspective on TLR structures

Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) that recognize conserved structures in pathogens, trigger innate immune responses and prime antigen-specific adaptive immunity. Elucidation of crystal structures of TLRs interacting with their ligands such as TLR1-2 with triacylated...

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Bibliographic Details
Main Authors: Balachandran eManavalan, Shaherin eBasith, Sangdun eChoi
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00041/full