Similar structures but different roles - An updated perspective on TLR structures
Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) that recognize conserved structures in pathogens, trigger innate immune responses and prime antigen-specific adaptive immunity. Elucidation of crystal structures of TLRs interacting with their ligands such as TLR1-2 with triacylated...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-07-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00041/full |