The Immune Privilege of Cancer Stem Cells: A Key to Understanding Tumor Immune Escape and Therapy Failure

The Immune Privilege of Cancer Stem Cells: A Key to Understanding Tumor Immune Escape and Therapy Failure

Cancer stem cells (CSCs) are broadly considered immature, multipotent, tumorigenic cells within the tumor mass, endowed with the ability to self-renew and escape immune control. All these features contribute to place CSCs at the pinnacle of tumor aggressiveness and (immune) therapy resistance. The i...

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Bibliographic Details
Main Authors: Claudia Galassi, Martina Musella, Nicoletta Manduca, Ester Maccafeo, Antonella Sistigu
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
tumor microenvironment
cancer stem cells
immunogenicity
immune escape
immunotherapy
Online Access:https://www.mdpi.com/2073-4409/10/9/2361

Internet

https://www.mdpi.com/2073-4409/10/9/2361

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