Induction of Endoplasmic Reticulum Stress and Unfolded Protein Response Constitutes a Pathogenic Strategy of group A Streptococcus
The connection between bacterial pathogens and unfolded protein response (UPR) is poorly explored. In this review we highlight the evidence showing that group A streptococcus (GAS) induces endoplasmic reticulum (ER) stress and UPR through which it captures the amino acid asparagine (ASN) from the ho...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2014-08-01
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Series: | Frontiers in Cellular and Infection Microbiology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00105/full |