Expression of P-glycoprotein, multidrug resistance-associated protein, glutathione-S-transferase pi and p53 in canine transmissible venereal tumor

The overexpression of proteins P-glycoprotein (P-gp), multidrug resistance-associated protein (MRP1), mutant p53, and the enzyme glutathione-S-transferase (GSTpi) are related to resistance to chemotherapy in neoplasms. This study evaluated the expression of these markers by immunohistochemistry in t...

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Bibliographic Details
Main Authors: Daniel G. Gerardi, Mirela Tinucci-Costa, Ana Carolina T. Silveira, Juliana V. Moro
Format: Article
Language:English
Published: Colégio Brasileiro de Patologia Animal (CBPA) 2014-01-01
Series:Pesquisa Veterinária Brasileira
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2014000100012&lng=en&tlng=en