Near-infrared fluorescence imaging of mammalian cells and xenograft tumors with SNAP-tag.

Fluorescence in the near-infrared (NIR) spectral region is suitable for in vivo imaging due to its reduced background and high penetration capability compared to visible fluorescence. SNAP(f) is a fast-labeling variant of SNAP-tag that reacts with a fluorescent dye-conjugated benzylguanine (BG) subs...

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Bibliographic Details
Main Authors: Haibiao Gong, Joy L Kovar, Brenda Baker, Aihua Zhang, Lael Cheung, Daniel R Draney, Ivan R Corrêa, Ming-Qun Xu, D Michael Olive
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316518?pdf=render