Application of a pharmacokinetics-pharmacodynamics approach to the free propofol plasma levels during coronary artery bypass grafting surgery with hypothermic cardiopulmonary bypass

Application of a pharmacokinetics-pharmacodynamics approach to the free propofol plasma levels during coronary artery bypass grafting surgery with hypothermic cardiopulmonary bypass

OBJECTIVES: The objective of this study was to apply a pharmacokinetics-pharmacodynamics approach to investigate the free propofol plasma levels in patients undergoing coronary artery bypass grafting under hypothermic conditions compared with the off-pump procedure. METHODS: Nineteen patients sched...

Full description

Bibliographic Details
Main Authors:	Carlos R. Silva-Filho, Ricardo Antonio G. Barbosa, Carlindo V. Silva-Jr, Luiz M.S. Malbouisson, Maria José C. Carmona, Silvia Regina C. Jorge-Santos
Format:	Article
Language:	English
Published:	Faculdade de Medicina / USP 2018-02-01
Series:	Clinics
Subjects:	Coronary Artery Bypass Cardiopulmonary Bypass Propofol Protein Binding Pharmacokinetics Pharmacodynamics
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322018000100202&lng=en&tlng=en

Similar Items

Effects of cardiopulmonary bypass on propofol pharmacokinetics and bispectral index during coronary surgery
by: Ricardo Antonio G. Barbosa, et al.
Published: (2009-03-01)

Cardiopulmonary bypass alters the pharmacokinetics of propranolol in patients undergoing cardiac surgery
by: M.J.C. Carmona, et al.
Published: (2005-05-01)

Effect of cardiopulmonary bypass on the pharmacokinetics of propranolol and atenolol
by: M.J.C. Carmona, et al.
Published: (2009-06-01)

Anti-inflammatory effects of propofol during cardiopulmonary bypass: A pilot study
by: A Samir, et al.
Published: (2015-01-01)

Cross-clamping of the descending thoracic aorta leads to the asymmetrical distribution of propofol during cardiopulmonary bypass surgery
by: Maiko Yamauchi-Satomoto, et al.
Published: (2012-04-01)

Effect of sevoflurane and propofol on cerebral oxygen metabolism in cardiopulmonary bypass and postoperative neurological function injury
by: Zhu Zhu, et al.
Published: (2016-12-01)

IMPACT OF ANESTHESIA WITH PROLONGED USE OF DESFLURANE AND SEVOFLURANE ON THE CARDIAC FUNCTION IN CORONARY ARTERY BYPASS GRAFT SURGERIES WITH CARDIOPULMONARY BYPASS
by: N. S. Molchan, et al.
Published: (2018-01-01)

The impact of general anesthesia on methionine metabolism during cardiopulmonary bypass
by: Yu. S. Polushin, et al.
Published: (2020-09-01)

Ultrafiltration Technology and Its Application in Cardiopulmonary Bypass
by: Zhang Kun, et al.
Published: (2017-01-01)

Features of Cardiopulmonary Bypass in Mininvasive Multivessel Coronary Artery Bypass Grafting
by: V. M. Demianenko, et al.
Published: (2019-05-01)

Biotransformation of nitroglycerin in blood and its bioavailability and pharmacokinetics during cardiopulmonary bypass/
by: Wu, Lei-Shu Chang
Published: (1983)

Successful management of hypothermic cardiopulmonary bypass in a malignant hyperthermia susceptible patient
by: Shvetank Agarwal, et al.
Published: (2020-01-01)

Myocardial damage in cardioplegia and cardiopulmonary bypass
by: M.Т. Vatutin, et al.
Published: (2016-05-01)

Emergency Conversion from Off Pump to Cardiopulmonary Bypass in Patients with Coronary Artery Bypass Graft Surgery
by: Kambiz Alizadeh, et al.
Published: (2013-08-01)

Emergency Conversion from Off Pump to Cardiopulmonary Bypass in Patients with Coronary Artery Bypass Graft Surgery
Published: (2013-08-01)

Comparison of blood electrolytes and glucose during cardiopulmonary bypass in diabetic and non-diabetic patients
by: Golamreza Maasoumi, et al.
Published: (2013-01-01)

Effect of cardiopulmonary bypass on tissue injury markers and endothelial activation during coronary artery bypass graft surgery
by: S Nair, et al.
Published: (2012-01-01)

Cardiopulmonary Bypass Induced Inflammation in Patients with Stable Angina
by: Rashad Mahmudov, et al.
Published: (2014-06-01)

Hypothermia and normothermia effects on mortality rate of cardiopulmonary bypass
by: Ali Rahdari, et al.
Published: (2015-12-01)

Computed tomography assessment of lung structure in patients undergoing cardiac surgery with cardiopulmonary bypass
by: R.R. Rodrigues, et al.
Published: (2011-06-01)

Computed tomography assessment of lung structure in patients undergoing cardiac surgery with cardiopulmonary bypass
by: R.R. Rodrigues, et al.
Published: (2011-06-01)

Basics of cardiopulmonary bypass
by: Manjula Sarkar, et al.
Published: (2017-01-01)

Ketamine has no effect on oxygenation indices following elective coronary artery bypass grafting under cardiopulmonary bypass
by: Parthasarathi Gayatri, et al.
Published: (2011-01-01)

A Thrombomodulin Gene Polymorphism (C1418T) Is Associated with Early Outcomes in Patients Undergoing Coronary Artery Bypass Graft Surgery with a Conventional Cardiopulmonary Bypass during Hospitalization
by: Ching-Chou Pai, et al.
Published: (2017-04-01)

Is it possible to augment myocardial protection during cardiopulmonary bypass by administration of inhalational anesthetics?
by: N. S. Molchan, et al.
Published: (2019-07-01)

Building and Application of Cardiopulmonary Bypass Model in Rats
by: Zhang Kun, et al.
Published: (2017-01-01)

Total cefazolin serum levels during elective valve replacement surgery on cardiopulmonary bypass
by: Calleemalay, Daren
Published: (2017)

Predictive value of rotational thromboelastometry during cardiopulmonary bypass for thrombocytopenia and hypofibrinogenemia after weaning of cardiopulmonary bypass
by: Sung-Mi Ji, et al.
Published: (2015-06-01)

Heparin Coating Technology in Cardiopulmonary Bypass
by: Zhang Kun, et al.
Published: (2017-01-01)

Cardiopulmonary Bypass Ischemic Hepatitis Reported in Five Patients
by: Telma A. Damasceno, et al.

PREDICTORS OF CONTINUOUS HOSPITAL STAY IN ADULT PATIENTS WITH ACQUIRED VALVULAR DISEASE, OPERATED WITH HYPOTHERMIC AND NORMOTHERMIC CARDIOPULMONARY BYPASS
by: D. G. Shakhin, et al.
Published: (2017-12-01)

Association between incidence of atrial fibrillation and duration of cardiopulmonary bypass in coronary artery bypass graft surgery (CABG): a cohort study
by: Maryam Rajabi,, et al.
Published: (2018-04-01)

Release of Cardiac Biomarkers and Inflammatory Response during Cardiopulmonary Bypass: Comparison of Different Biocompatible Materials Used in Cardiopulmonary Bypass
by: Sohn, Namseok
Published: (2008)

Comparison of Early Outcomes for Normothermic and Hypothermic Cardiopulmonary Bypass in Children Undergoing Congenital Heart Surgery
by: Antonio F. Corno, et al.
Published: (2018-08-01)

USE OF INHALATION ANESTHETICS DURING CARDIOPULMONARY BYPASS
by: E. Yu. Chepurnyak, et al.
Published: (2018-08-01)

Postoperative abdominal complications after cardiopulmonary bypass
by: Dong Guohua, et al.
Published: (2012-10-01)

Effect of cardiopulmonary bypass on hemostasis in patients undergoing cardiac surgery
by: Jubayer Ahmad, et al.
Published: (2018-05-01)

Managament of Conversions to Cardiopulmonary Bypass in Beating Heart Coronary Surgery
by: Emir Mujanović, et al.
Published: (2008-08-01)

Consequence of Ischemic Stroke after Coronary Surgery with Cardiopulmonary Bypass According to Stroke Subtypes
by: Mustafa Aldag, et al.

Comparison of ringer's lactate and plasmalyt-a as cardiopulmonary bypass prime for bypass associated acidosis in valve replacement surgeries
by: Sandill Surabhi, et al.
Published: (2021-01-01)