Dependency of the Cancer-Specific Transcriptional Regulation Circuitry on the Promoter DNA Methylome

Summary: Dynamic dysregulation of the promoter DNA methylome is a signature of cancer. However, comprehensive understandings about how the DNA methylome is incorporated in the transcriptional regulation circuitry and involved in regulating the gene expression abnormality in cancers are still missing...

Full description

Bibliographic Details
Main Authors: Yu Liu, Yang Liu, Rongyao Huang, Wanlu Song, Jiawei Wang, Zhengtao Xiao, Shengcheng Dong, Yang Yang, Xuerui Yang
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719302700