Ethanol-Induced Oxidative Stress Modifies Inflammation and Angiogenesis Biomarkers in Retinal Pigment Epithelial Cells (ARPE-19): Role of CYP2E1 and its Inhibition by Antioxidants

Ethanol-Induced Oxidative Stress Modifies Inflammation and Angiogenesis Biomarkers in Retinal Pigment Epithelial Cells (ARPE-19): Role of CYP2E1 and its Inhibition by Antioxidants

The retinal pigment epithelium (RPE) plays a key role in retinal health, being essential for the protection against reactive oxygen species (ROS). Nevertheless, excessive oxidative stress can induce RPE dysfunction, promoting visual loss. Our aim is to clarify the possible implication of CYP2E1 in e...

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Bibliographic Details
Main Authors: Natalia Martinez-Gil, Lorena Vidal-Gil, Miguel Flores-Bellver, Rosa Maisto, Javier Sancho-Pelluz, Manuel Diaz-Llopis, Jorge M. Barcia, Francisco J. Romero
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Antioxidants
Subjects:
retinal pigment epithelium
homeostasis
oxidative stress
degeneration
CYP2E1
Online Access:https://www.mdpi.com/2076-3921/9/9/776

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https://www.mdpi.com/2076-3921/9/9/776

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