A computational model for gonadotropin releasing cells in the teleost fish medaka.

Pituitary endocrine cells fire action potentials (APs) to regulate their cytosolic Ca2+ concentration and hormone secretion rate. Depending on animal species, cell type, and biological conditions, pituitary APs are generated either by TTX-sensitive Na+ currents (INa), high-voltage activated Ca2+ cur...

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Bibliographic Details
Main Authors: Geir Halnes, Simen Tennøe, Trude M Haug, Gaute T Einevoll, Finn-Arne Weltzien, Kjetil Hodne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1006662