Bioassay-directed fractionation of a blood coagulation factor Xa inhibitor, betulinic acid from Lycopus lucidus

Thrombosis is a major cause of morbidity and mortality worldwide and plays a pivotal role in the pathogenesis of several cardiovascular disorders, including acute coronary syndrome, unstable angina, myocardial infarction, sudden cardiac death, peripheral arterial occlusion, ischemic stroke, deep-vei...

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Bibliographic Details
Main Authors: Tan Yin-Feng, Wang Qiong, Gong Jing-Wen, Zhang Xu-Guang, Li Yong-Hui, Zhang Jun-Qing, Li You-Bin
Format: Article
Language:English
Published: De Gruyter 2018-03-01
Series:Open Chemistry
Subjects:
Online Access:https://doi.org/10.1515/chem-2018-0018