PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.

PDlim2 selectively interacts with the PDZ binding motif of highly pathogenic avian H5N1 influenza A virus NS1.

The multi-functional NS1 protein of influenza A virus is a viral virulence determining factor. The last four residues at the C-terminus of NS1 constitute a type I PDZ domain binding motif (PBM). Avian influenza viruses currently in circulation carry an NS1 PBM with consensus sequence ESEV, whereas h...

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Bibliographic Details
Main Authors: Jia Yu, Xin Li, Yu Wang, Bo Li, Hongyue Li, Yapeng Li, Weihong Zhou, Cuizhu Zhang, Yingying Wang, Zihe Rao, Mark Bartlam, Youjia Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625420/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625420/?tool=EBI

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